| Final 19:24 | time | | | 1. Ye Shiwen |  CHN | 4:32.97 | GR | | 2. Sakiko Shimizu |  JPN | 4:38.63 | | | 3. Nguyễn Thị Ánh Viên |  VIE | 4:39.65 | | | 4. Kim Seo-yeong |  KOR | 4:42.92 | | | 5. Miho Takahashi | JPN | 4:43.61 | | | 6. Zhou Min | CHN | 4:44.49 | | | 7. Nam Yoo-sun | KOR | 4:44.61 | | | 8. Ranohon Amanova |  UZB | 4:48.99 | |
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| Venue: Muhak Park Tae-hwan Aquatics Center. |
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| World record: Ye Shiwen (CHN) 4:28.43 London, United Kingdom 28 July 2012 | | Asian record: Ye Shiwen (CHN) 4:28.43 London, United Kingdom 28 July 2012 | | Games record: Ye Shiwen (CHN) 4:33.79 Guangzhou, China 14 November 2010 |
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Heats - Tuesday 23.09 Morning session 09:00 |
| Ranking | time | H | | 1. Ye Shiwen | CHN | 4:38.21 | 2 | | 2. Sakiko Shimizu | JPN | 4:40.49 | 1 | | 3. Kim Seo-yeong | KOR | 4:44.27 | 1 | | 4. Nam Yoo-sun | KOR | 4:45.82 | 1 | | 5. Zhou Min | CHN | 4:46.12 | 2 | | 6. Miho Takahashi | JPN | 4:46.58 | 1 | | 7. Nguyễn Thị Ánh Viên | VIE | 4:46.77 | 2 | | 8. Ranohon Amanova | UZB | 4:50.74 | 2 | | eliminated in Heats | | 9. Sarisa Suwannachet |  THA | 4:58.30 | 2 | | 10.Tan Jing E |  SGP | 5:05.62 | 1 | | 11.Gabriella Doueihy |  LBN | 5:32.27 | 2 |
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