| Final A | Team | time | -)time | L | React. | 50m | 100m | 150m | | 1. Elizabeth Anne Pelton | --- | 2:08.99 | RP | 4 | 0.62s | 1. | 30.09s | 1. | 1:02.63 | 1. | 1:35.52 | | 2. Bonnie Brandon | --- | 2:12.57 | 3.58s | 5 | 0.74s | 3. | 31.09s | 2. | 1:04.35 | 2. | 1:38.52 | | 3. Fernanda Gonzalez | --- | 2:13.56 | 4.57s | 3 | 0.63s | 4. | 31.25s | 4. | 1:04.64 | 3. | 1:38.98 | | 4. Gisela Maria Morales | --- | 2:16.33 | 7.34s | 7 | 0.69s | 2. | 30.79s | 3. | 1:04.53 | 4. | 1:39.58 | | 5. Lourdes Villasenor | --- | 2:16.60 | 7.61s | 6 | 0.72s | 7. | 32.22s | 6. | 1:06.86 | 6. | 1:42.75 | | 6. Gabrielle Soucisse | --- | 2:16.86 | 7.87s | 2 | 0.76s | 5. | 31.61s | 5. | 1:05.92 | 5. | 1:41.12 | | 7. Elimar Barrios | --- | 2:21.40 | 12.41s | 1 | 0.67s | 8. | 33.04s | 8. | 1:08.45 | 8. | 1:45.20 | | 8. Fernanda Alvarenga | --- | 2:22.77 | 13.78s | 8 | 0.67s | 6. | 32.03s | 7. | 1:06.98 | 7. | 1:44.05 |
| Final B | Team | time | -)time | L | React. | 50m | 100m | 150m | | 9. Mckayla Lightbourn | --- | 2:19.25 | | 4 | 0.68 | 3. | 32.64 | 1. | 1:07.45 | 1. | 1:43.05 | | 10.Karyn Jewell | --- | 2:20.87 | 1.62 | 5 | 0.62 | 4. | 32.69 | 2. | 1:07.78 | 2. | 1:44.62 | | 11.Florencia Perotti | --- | 2:23.03 | 3.78 | 6 | 0.69 | 1. | 32.39 | 3. | 1:07.88 | 3. | 1:45.70 | | 12.Ines Remersaro | --- | 2:24.16 | 4.91 | 8 | 0.69 | 7. | 33.36 | 7. | 1:09.89 | 5. | 1:47.38 | | 13.Alana Berrocal | --- | 2:24.18 | 4.93 | 3 | 0.67 | 2. | 32.61 | 4. | 1:09.13 | 4. | 1:46.95 | | 14.Erika Torellas | --- | 2:25.17 | 5.92 | 2 | 0.64 | 8. | 33.65 | 8. | 1:10.58 | 7. | 1:48.18 | | 15.Karen Vilorio | --- | 2:25.99 | 6.74 | 7 | 0.58 | 6. | 33.16 | 5. | 1:09.61 | 6. | 1:47.41 | | 16.Laura Rodriguez | --- | 2:28.13 | 8.88 | 1 | 0.61 | 5. | 33.13 | 6. | 1:09.73 | 8. | 1:48.19 |
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| World record: | | Pan American Games record: |
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| Qualification: | | Standard A: 2:22.8 | | Standard B: 2:27.1 |
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| Heats | Team | time | -)time | L | React. | 50m | 100m | 150m | Heat | | 1. Elizabeth Anne Pelton | --- | 2:10.66 | | 4 | 0.65s | 1. | 30.50s | 1. | 1:03.30 | 1. | 1:36.70 | Heat 3. | | 2. Bonnie Brandon | --- | 2:13.87 | 3.21s | 4 | 0.78s | 1. | 31.22s | 1. | 1:04.37 | 1. | 1:38.62 | Heat 2. | | 3. Fernanda Gonzalez | --- | 2:16.61 | 5.95s | 4 | 0.64s | 1. | 31.77s | 1. | 1:06.37 | 1. | 1:41.94 | Heat 1. | | 4. Lourdes Villasenor | --- | 2:16.94 | 6.28s | 5 | 0.67s | 2. | 32.91s | 2. | 1:07.55 | 2. | 1:42.88 | Heat 1. | | 5. Gabrielle Soucisse | --- | 2:17.27 | 6.61s | 5 | 0.71s | 2. | 32.07s | 2. | 1:06.62 | 2. | 1:41.93 | Heat 2. | | 6. Gisela Maria Morales | --- | 2:17.86 | 7.20s | 5 | 0.67s | 2. | 32.14s | 2. | 1:06.74 | 2. | 1:42.18 | Heat 3. | | 7. Elimar Barrios | --- | 2:20.96 | 10.30s | 6 | 0.66s | 3. | 33.75s | 3. | 1:09.54 | 3. | 1:45.86 | Heat 2. | | 8. Fernanda Alvarenga | --- | 2:21.24 | 10.58s | 3 | 0.72s | 3. | 32.32s | 3. | 1:06.90 | 3. | 1:43.32 | Heat 3. | | 9. Mckayla Lightbourn | --- | 2:23.74 | 13.08s | 2 | 0.69s | 5. | 33.09s | 5. | 1:08.66 | 4. | 1:46.22 | Heat 3. | | 10.Karyn Jewell | --- | 2:23.78 | 13.12s | 3 | 0.62s | 6. | 33.75s | 4. | 1:09.31 | 3. | 1:46.58 | Heat 1. | | 11.Alana Berrocal | --- | 2:24.76 | 14.10s | 6 | 0.69s | 4. | 33.38s | 6. | 1:10.06 | 4. | 1:47.66 | Heat 1. | | 12.Florencia Perotti | --- | 2:24.78 | 14.12s | 6 | 0.73s | 4. | 32.95s | 4. | 1:08.56 | 5. | 1:46.48 | Heat 3. | | 13.Erika Torellas | --- | 2:26.16 | 15.50s | 2 | 0.64s | 5. | 34.00s | 5. | 1:11.07 | 5. | 1:49.29 | Heat 2. | | 14.Karen Vilorio | --- | 2:26.58 | 15.92s | 7 | 0.60s | 4. | 33.82s | 4. | 1:10.81 | 4. | 1:48.43 | Heat 2. | | 15.Laura Rodriguez | --- | 2:27.26 | 16.60s | 7 | 0.60s | 6. | 33.71s | 6. | 1:09.95 | 6. | 1:48.82 | Heat 3. | | 16.Ines Remersaro | --- | 2:27.77 | 17.11s | 2 | 0.72s | 3. | 33.03s | 3. | 1:09.27 | 6. | 1:48.04 | Heat 1. | | 17.Mariana Zavalla | --- | 2:28.30 | 17.64s | 7 | 0.61s | 5. | 33.52s | 5. | 1:09.85 | 5. | 1:47.68 | Heat 1. | | -. Joanna Maranhao | --- | DNS | | 3 | | | | | | | | Heat 2. |
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