| date | time | team 1 ____________ | score | team 2 ____________ | HT | |
| Tue 20.10.20 | 15:00 | Kariana Erden (II) | 0-1 | Tsarsko Selo Sofia | 0-0 | |
| Wed 21.10.20 | 14:30 | Partizan Cherven Bryag (III) | 1-4 | Levski Sofia | 1-2 | |
| Wed 21.10.20 | 15:00 | FC Sevlievo (III) | 1-5 | Slavia Sofia | 1-1 | |
| Wed 21.10.20 | 15:00 | Izvor Gorski Izvor (III) | 1-2 | Montana | 0-0 | |
| Wed 21.10.20 | 15:00 | Yantra Gabrovo (II) | 1-6 | Cherno More Varna | 1-2 | |
| Wed 21.10.20 | 15:00 | FK Drenovets (III) | 0-6 | CSKA 1948 Sofia | 0-5 | |
| Wed 21.10.20 | 17:30 | Pirin Blagoevgrad (II) | 3-4 | Beroe Stara Zagora | 2-1 | |
| Thu 22.10.20 | 15:00 | Chernomorets Balchik (III) | 1-0 | Septemvri Sofia (II) | 1-0 | |
| Thu 22.10.20 | 15:00 | Nadezhda Dobroslavtsi (III) | 0-2 | Botev Vratsa | 0-2 | |
| Thu 22.10.20 | 15:00 | Oborishte Panagyutiste (III) | 0-4 | Botev Plovdiv | 0-2 | |
| Thu 22.10.20 | 15:00 | Sozopol (II) | 0-02-4p | Etar Veliko Tarnovo | 0-0, 0-0 | |
| Tue 03.11.20 | 13:30 | Zagorets Nova Zagora (III) | 3-4aet | Lokomotiv Plovdiv | 1-2, 2-2 | |
| Wed 04.11.20 | 13:30 | Spartak Varna (III) | 1-2 | Arda Kardzhali | 0-1 | |
| Thu 11.02.21 | 14:30 | Ludogorets Razgrad | 3-1 | Sportist Svoge (II) | 1-0 | |
| postponned from Friday 13.11.2020 13:30. Home groupnd was changed. |
| Sat 14.11.20 | 13:30 | Botev Ihtiman (III) | 0-5 | CSKA Sofia | 0-2 | |
| played at Balgarska Armiya stadium, Sofia. |
| | | Belasitsa Petrich (III) | bye |
1-0 Bismark Charles 85' Vasil Levski Stadium.